| Batter | M | Inns | Runs | Ave | HS | |
|---|
| Thapelo Modise | 7 | 7 | 97 | 19.40 | 61 | v Kenya, 9 Jun 2022, IPRC Cricket Stadium |
| Florence Samanyika | 8 | 8 | 93 | 11.63 | 41 | v Germany, 17 June 2022, Gahanga Cricket Stadium |
| Olebogeng Batisani | 8 | 8 | 81 | 10.13 | 28 | v Germany, 17 Jun 2022, Gahanga Cricket Stadium |
| Shameelah Mosweu | 6 | 6 | 72 | 14.40 | 24 | v Nigeria, 11 Jun, IPRC Cricket Stadium |
| Laura Mophakedi | 8 | 8 | 64 | 8.13 | 22 | v Rwanda, 15 June 2022, Gahanga Cricket Stadium |
| Tuelo Shadrack | 8 | 8 | 52 | 8.67 | 26 | v Nigeria, 11 Jun, IPRC Cricket Stadium |
| Goabilwe Matome | 8 | 8 | 49 | 8.17 | 20 | v Rwanda, 15 June 2022, Gahanga Cricket Stadium |
| Oratile Kgeresi | 7 | 5 | 27 | 5.40 | 16 | v Germany, 14 Jun 2022, Gahanga Cricket Stadium |
| Thandiwe Legabile | 8 | 5 | 26 | 8.67 | 12 | v Tanzania, 10 Jun, IPRC Cricket Stadium |
| Mimmie Ramafifi | 6 | 4 | 11 | 3.67 | 6 | v Germany, 14 Jun 2022, Gahanga Cricket Stadium |
| Tebogo Motlhabaphuti | 7 | 5 | 10 | 3.33 | 9 | v Germany, 14 Jun 2022, Gahanga Cricket Stadium |
| Onneile Keitsemang | 6 | 3 | 3 | 1.50 | 3 | v Germany, 14 Jun 2022, Gahanga Cricket Stadium |